The 2022 Nordic Medac Grant has been awarded to Fredrik Liedberg, professor Department of Urology, ITM, Lund University, Skåne University Hospital, Sweden to support conduction of the study with the following title:
Study protocol for a Nordic multicenter study “Lymphadenectomy in upper tract urothelial carcinoma in the renal pelvis/calyces” (Lurp Study)
The indications for and extent of lymphadenectomy during surgery for upper tract urothelial carcinomas (UTUC) are hampered by the lack of evidence in a rare disease. The introduction of adjuvant chemotherapy in locally advanced UTUC (cT3 and/or N+) has further strengthened the indication to assess lymph node status and perform a template-based lymphadenectomy.Thus, we undertake a prospective template-based lymphadenectomy in patients with clinically advanced UTUC in the renal pelvis or upper 2/3 of the ureter in a Nordic multicentre setting with the primary endpoint location of lymph node metastases at surgery. Secondary aims are to further define preoperative predictors of lymph node metastases and assess surgery-related complications within 90 days.